The Denver Nuggets are once again in a must-win situation tonight, hosting the Los Angeles Lakers in Game 6 of the NBA first round playoff series in the Pepsi Center at 8:30 MT (TV: Attitude/TNT). The Lakers lead the best-of-seven series 3-2. A Nuggets win would force a Game 7 Saturday night back in Los Angeles.

The Nuggets will try to run L.A. ragged again Thursday night in Game 6 back in Denver, where the mile-high altitude can be a big fatigue factor for a team long in the tooth like the star-studded Lakers.

It worked great at sea level Tuesday night with elder statesman Andre Miller feeding raw 7-foot center JaVale McGee, whose athleticism and mind-boggling array of dunks made L.A.'s two 7-footers look like they were moving in slow motion.

And Denver coach George Karl is counting on the altitude helping the Nuggets contain Kobe Bryant, Andrew Bynum and Pau Gasol to force a Game 7 back in Los Angeles. He said there's wear and tear at 5,280 feet even if visitors downplay it or even deny it.

"My hope, I don't know if this is true or not, is that fatigue will come our way," Karl said. "The running of the game, the tempo of the game, and the pace, the way we play. They're getting tired of hearing it, and you're probably tired of hearing it, but our only chance to beat them is run them and play with tremendous energy and intensity. Maybe somewhere along the way, we'll make some 3s."

Tickets are available for tonight’s round-1 playoff game at Pepsi Center vs. the Los Angeles Lakers, and can be purchased by calling (303) 405-1111, or click here.